Michael Lee

[email protected]

+1 415 430-7676

Publications:

Reprogramming human T cell function and specificity with non-viral genome targeting.

Type 1 diabetes immunotherapy using polyclonal regulatory T cells.

Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes.

Human antigen-specific regulatory T cells generated by T cell receptor gene transfer.

Successful clinical islet isolation using a GMP-manufactured collagenase and neutral protease.

T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function.

Expansion of human regulatory T-cells from patients with type 1 diabetes.

Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice.

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells.